Bismuth Subcitrate Potassium, Metronidazole And Tetracycline Hydrochloride has 14 known drug interactions based on U.S. FDA drug labeling data. Of these, 2 are contraindicated combinations that should be avoided entirely. 5 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Alcohol, Disulfiram, Busulfan. Patients taking Bismuth Subcitrate Potassium, Metronidazole And Tetracycline Hydrochloride should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 14
- Contraindicated
- 2
- Major
- 5
- Moderate
- 6
Contraindicated (2)
- Bismuth Subcitrate Potassium, Metronidazole And Tetracycline Hydrochloride + Alcohol— Disulfiram-like reaction with abdominal cramps, nausea, vomiting, headaches, and flushing; do not consume during therapy…
- Bismuth Subcitrate Potassium, Metronidazole And Tetracycline Hydrochloride + Disulfiram— Psychotic reactions can occur; do not take concurrently or within the last 2 weeks of disulfiram.
Major (5)
- Bismuth Subcitrate Potassium, Metronidazole And Tetracycline Hydrochloride + Busulfan— Increased busulfan serum concentrations; avoid concomitant use and monitor for busulfan toxicity.
- Bismuth Subcitrate Potassium, Metronidazole And Tetracycline Hydrochloride + Lithium— Increased lithium serum concentrations; measure serum lithium and serum creatinine concentrations during therapy.
- Bismuth Subcitrate Potassium, Metronidazole And Tetracycline Hydrochloride + Oral Anticoagulants— Potentiation of anticoagulant effect; Prothrombin time, INR, or other anticoagulation tests should be closely monitored.
- Bismuth Subcitrate Potassium, Metronidazole And Tetracycline Hydrochloride + Oral Contraceptives— Decreased efficacy possibly resulting in pregnancy and breakthrough bleeding; use a different or additional form of cont…
- Bismuth Subcitrate Potassium, Metronidazole And Tetracycline Hydrochloride + Warfarin— Potentiation of anticoagulant effect with prolongation of prothrombin time; closely monitor prothrombin time, INR, and m…
Moderate (6)
- Bismuth Subcitrate Potassium, Metronidazole And Tetracycline Hydrochloride + Antacids Containing Calcium— Decreased absorption of the triple therapy capsules; do not take concomitantly.
- Bismuth Subcitrate Potassium, Metronidazole And Tetracycline Hydrochloride + Cyp3a Inducers— Prolonged or accelerated half-life of metronidazole or concomitant medications; use with caution.
- Bismuth Subcitrate Potassium, Metronidazole And Tetracycline Hydrochloride + Dairy Products— Decreased absorption of the triple therapy capsules; do not take concomitantly.
- Bismuth Subcitrate Potassium, Metronidazole And Tetracycline Hydrochloride + Mao Inhibitors— Prolonged or accelerated half-life of metronidazole or concomitant medications; use with caution.
- Bismuth Subcitrate Potassium, Metronidazole And Tetracycline Hydrochloride + Metronidazole— ( 5.14 , 7.5 ) Antacids, Multivitamins or Dairy Products: Decreased absorption of Bismuth Subcitrate Potassium, Metronid…
- Bismuth Subcitrate Potassium, Metronidazole And Tetracycline Hydrochloride + Multivitamin— Decreased absorption of the triple therapy capsules; do not take concomitantly.