Ombitasvir has 24 known drug interactions based on U.S. FDA drug labeling data. Of these, 6 are contraindicated combinations that should be avoided entirely. 1 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Desogestrel And Ethinyl Estradiol And Ethinyl Estradiol, Levonorgestrel And Ethinyl Estradiol And Ethinyl Estradiol Tablets, Levonorgestrel/Ethinyl Estradiol And Ethinyl Estradiol. Patients taking Ombitasvir should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 24
- Contraindicated
- 6
- Major
- 1
- Moderate
- 2
Contraindicated (6)
- Ombitasvir + Desogestrel And Ethinyl Estradiol And Ethinyl Estradiol— Concomitant Use with Hepatitis C Virus (HCV) Combination Therapy - Liver Enzyme Elevation Co-administration of VIORELE ®…
- Ombitasvir + Levonorgestrel And Ethinyl Estradiol And Ethinyl Estradiol Tablets— 7.3 Concomitant Use with Hepatitis C Virus (HCV) Combination Therapy – Liver Enzyme Elevation Co-administration of levon…
- Ombitasvir + Levonorgestrel/Ethinyl Estradiol And Ethinyl Estradiol— 7.3 Concomitant Use with Hepatitis C Virus (HCV) Combination Therapy – Liver Enzyme Elevation Co-administration of Simpe…
- Ombitasvir + Norethindrone Acetate, Ethinyl Estradiol And Ferrous Fumarate— Concomitant Use with HCV Combination Therapy – Liver Enzyme Elevation Co-administration of Tarina Fe 1/20 EQ with HCV dr…
- Ombitasvir + Norethindrone Acetate/Ethinyl Estradiol— Concomitant Use with HCV Combination Therapy - Liver Enzyme Elevation Co-administration of norethindrone acetate and eth…
- Ombitasvir + Norethindrone And Ethinyl Estradiol— Do not co-administer norethindrone and ethinyl estradiol with HCV drug combinations containing ombitasvir/paritaprevir/r…
Major (1)
- Ombitasvir + Rosuvastatin— Intervention: • Sofosbuvir/velpatasvir/voxilaprevir • Ledipasvir/sofosbuvir Avoid concomitant use with rosuvastatin • Si…
Moderate (2)
- Ombitasvir + Itraconazole— Cobicistat Elvitegravir (ritonavir-boosted) Ombitasvir/Paritaprevir/Ritonavir with or without Dasabuvir Ritonavir Saquin…
- Ombitasvir + Rydapt— Strong CYP3A4 inhibitor that may increase midostaurin concentrations and risk of toxicity. Monitor for increased adverse…