Hydrocodone Bitartrate And Homatropine Methylbromide Oral Solution has 12 known drug interactions based on U.S. FDA drug labeling data. Of these, 1 are contraindicated combinations that should be avoided entirely. 6 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Alcohol, Erythromycin, Ketoconazole. Patients taking Hydrocodone Bitartrate And Homatropine Methylbromide Oral Solution should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 12
- Contraindicated
- 1
- Major
- 6
- Moderate
- 4
Contraindicated (1)
- Hydrocodone Bitartrate And Homatropine Methylbromide Oral Solution + Alcohol— Concomitant use can result in increased hydrocodone plasma levels and potentially fatal overdose. Patients should not co…
Major (6)
- Hydrocodone Bitartrate And Homatropine Methylbromide Oral Solution + Erythromycin— CYP3A4 inhibitor that can increase hydrocodone plasma concentration, resulting in increased or prolonged opioid effects …
- Hydrocodone Bitartrate And Homatropine Methylbromide Oral Solution + Ketoconazole— Azole-antifungal CYP3A4 inhibitor that can increase hydrocodone plasma concentration, resulting in increased or prolonge…
- Hydrocodone Bitartrate And Homatropine Methylbromide Oral Solution + Methylbromide— 7 DRUG INTERACTIONS No specific drug interaction studies have been conducted with hydrocodone bitartrate and homatropine…
- Hydrocodone Bitartrate And Homatropine Methylbromide Oral Solution + Monoamine Oxidase Inhibitors (Maois)— Can potentiate the effects of hydrocodone. Avoid concomitant use in patients receiving MAOIs or within 14 days of stoppi…
- Hydrocodone Bitartrate And Homatropine Methylbromide Oral Solution + Muscle Relaxants— Avoid concomitant use with hydrocodone bitartrate and homatropine methylbromide.
- Hydrocodone Bitartrate And Homatropine Methylbromide Oral Solution + Ritonavir— Protease inhibitor and CYP3A4 inhibitor that can increase hydrocodone plasma concentration, resulting in increased or pr…
Moderate (4)
- Hydrocodone Bitartrate And Homatropine Methylbromide Oral Solution + Carbamazepine— CYP3A4 inducer that can decrease hydrocodone plasma concentration, resulting in decreased efficacy or withdrawal syndrom…
- Hydrocodone Bitartrate And Homatropine Methylbromide Oral Solution + Diuretics— Hydrocodone may reduce the efficacy of diuretics. Monitor for reduced effect.
- Hydrocodone Bitartrate And Homatropine Methylbromide Oral Solution + Phenytoin— CYP3A4 inducer that can decrease hydrocodone plasma concentration, resulting in decreased efficacy or withdrawal syndrom…
- Hydrocodone Bitartrate And Homatropine Methylbromide Oral Solution + Rifampin— CYP3A4 inducer that can decrease hydrocodone plasma concentration, resulting in decreased efficacy or withdrawal syndrom…