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Desmethyldiazepam

11 interactions on record

Desmethyldiazepam has 11 known drug interactions based on U.S. FDA drug labeling data. Patients taking Desmethyldiazepam should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.

Total: 11
Minor: 2

Minor (2)

Desmethyldiazepam + Buspirone— Diazepam After addition of buspirone to the diazepam dose regimen, no statistically significant differences in the stead…
Desmethyldiazepam + Buspirone Hydrochloride— Diazepam: After addition of buspirone to the diazepam dose regimen, no statistically significant differences in the stea…

Desmethyldiazepam + Buspirone🟢Minor

Diazepam After addition of buspirone to the diazepam dose regimen, no statistically significant differences in the steady-state pharmacokinetic parameters (C max , AUC, and C min ) were observed for diazepam, but increases of about 15% were seen for nordiazepam, and minor adverse clinical effects (dizziness, headache, and nausea) were observed.

Desmethyldiazepam + Buspirone Hydrochloride🟢Minor

Diazepam: After addition of buspirone to the diazepam dose regimen, no statistically significant differences in the steady-state pharmacokinetic parameters (C max , AUC, and C min ) were observed for diazepam, but increases of about 15% were seen for nordiazepam, and minor adverse clinical effects (dizziness, headache, and nausea) were observed.

Desmethyldiazepam + Clorazepate Dipotassiumℹ️Unknown

Nursing Mothers Risk Summary Clorazepate and its active metabolite, nordiazepam, are present in breast milk.

Desmethyldiazepam + Olanzapineℹ️Unknown

Diazepam — Olanzapine did not influence the pharmacokinetics of diazepam or its active metabolite N-desmethyldiazepam.

Desmethyldiazepam + Olanzapine And Fuoxetineℹ️Unknown

Benzodiazepines — Multiple doses of olanzapine did not influence the pharmacokinetics of diazepam and its active metabolite N-desmethyldiazepam.

Desmethyldiazepam + Olanzapine Pamoateℹ️Unknown

Diazepam — Olanzapine did not influence the pharmacokinetics of diazepam or its active metabolite N-desmethyldiazepam.

Desmethyldiazepam + Sertralineℹ️Unknown

There was a 23% increase in T max for desmethyldiazepam in the sertraline group compared to a 20% decrease in the placebo group (p<0.03).

Desmethyldiazepam + Sertraline Hydrochlorideℹ️Unknown

There was a 23% increase in T max for desmethyldiazepam in the sertraline hydrochloride group compared to a 20% decrease in the placebo group (p<0.03).

Desmethyldiazepam + Venlafaxineℹ️Unknown

Venlafaxine also did not have any effect on the pharmacokinetics of diazepam or its active metabolite, desmethyldiazepam, or affect the psychomotor and psychometric effects induced by diazepam.

Desmethyldiazepam + Venlafaxine Hcl Erℹ️Unknown

Venlafaxine also did not have any effect on the pharmacokinetics of diazepam or its active metabolite, desmethyldiazepam, or affect the psychomotor and psychometric effects induced by diazepam.

Desmethyldiazepam + Venlafaxine Hydrochlorideℹ️Unknown

Venlafaxine also did not have any effect on the pharmacokinetics of diazepam or its active metabolite, desmethyldiazepam, or affect the psychomotor and psychometric effects induced by diazepam.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.