Terazosin has 31 known drug interactions based on U.S. FDA drug labeling data. 2 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Midodrine Hydrochloride, Vardenafil, Propranolol Hydrochloride. Patients taking Terazosin should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 31
- Major
- 2
- Moderate
- 3
- Minor
- 23
Major (2)
- Terazosin + Midodrine Hydrochloride— Alpha-adrenergic blocking agent can antagonize the effects of midodrine hydrochloride.
- Terazosin + Vardenafil— Alpha-blocker interaction with additive blood pressure lowering effects. Clinical pharmacology studies conducted; cautio…
Moderate (3)
- Terazosin + Propranolol Hydrochloride— Postural hypotension reported in patients taking both beta-blockers and terazosin.
- Terazosin + Vardenafil Hydrochloride— Caution is advised when vardenafil is co-administered with terazosin. Both are vasodilators with blood-pressure-lowering…
- Terazosin + Verapamil— Verapamil increases terazosin AUC by 11-24%, Cmax by 25%, and Cmin by 32% after 3 weeks of concomitant use, with decreas…
Minor (23)
- Terazosin + Acetaminophen— Terazosin has been used concomitantly with acetaminophen in at least 50 patients with no interactions observed.
- Terazosin + Acetylsalicylic Acid— Terazosin has been used concomitantly with aspirin in at least 50 patients with no interactions observed.
- Terazosin + Allopurinol— Terazosin has been used concomitantly with allopurinol in at least 50 patients with no interactions observed.
- Terazosin + Atenolol— Terazosin has been added to atenolol in controlled trials with no unexpected interactions observed.
- Terazosin + Captopril— Concomitant administration of captopril does not influence captopril plasma disposition; terazosin maximum plasma concen…
- Terazosin + Chlorpheniramine— Terazosin has been used concomitantly with chlorpheniramine in at least 50 patients with no interactions observed.
- Terazosin + Codeine— Terazosin has been used concomitantly with codeine in at least 50 patients with no interactions observed.
- Terazosin + Diazepam— Terazosin has been used concomitantly with diazepam in at least 50 patients with no interactions observed.
- Terazosin + Diuretics— Terazosin added to diuretics in controlled trials with no unexpected interactions observed.
- Terazosin + Dutasteride— Administration of dutasteride in combination with terazosin has no effect on the steady-state pharmacokinetics of terazo…
- Terazosin + Erythromycin— Terazosin has been used concomitantly with erythromycin in at least 50 patients with no interactions observed.
- Terazosin + Hydrochlorothiazide— Terazosin has been added to hydrochlorothiazide in controlled trials with no unexpected interactions observed.
- Terazosin + Ibuprofen— Terazosin has been used concomitantly with ibuprofen in at least 50 patients with no interactions observed.
- Terazosin + Indomethacin— Terazosin has been used concomitantly with indomethacin in at least 50 patients with no interactions observed.
- Terazosin + Methyclothiazide— Terazosin has been used concomitantly with methyclothiazide in at least 50 patients with no interactions observed.
- Terazosin + Nonselective Beta-Adrenergic Antagonists— Terazosin has been combined with several beta-adrenergic blockers in controlled trials with no unexpected interactions o…
- Terazosin + Phenylephrine Hydrochloride— Terazosin has been used concomitantly with phenylephrine hydrochloride in at least 50 patients with no interactions obse…
- Terazosin + Phenylpropanolamine Hydrochloride— Terazosin has been used concomitantly with phenylpropanolamine hydrochloride in at least 50 patients with no interaction…
- Terazosin + Propranolol— Terazosin has been added to propranolol in controlled trials with no unexpected interactions observed.
- Terazosin + Pseudoephedrine Hydrochloride— Terazosin has been used concomitantly with pseudoephedrine hydrochloride in at least 50 patients with no interactions ob…
- Terazosin + Sulfamethoxazole— Terazosin has been used concomitantly with sulfamethoxazole in at least 50 patients with no interactions observed.
- Terazosin + Sulfamethoxazole And Trimethoprim— Used concomitantly in at least 50 patients with no interactions observed.
- Terazosin + Trimethoprim— Terazosin has been used concomitantly with trimethoprim in at least 50 patients with no interactions observed.