Darunavir%2C Cobicistat%2C Emtricitabine%2C And Tenofovir Alafenam + Oxycodone Interaction
Majorinteraction on record
Description
Narcotic analgesics metabolized by CYP3A: e.g., fentanyl, oxycodone ↑ fentanyl ↑ oxycodone Careful monitoring of therapeutic effects and adverse reactions associated with CYP3A-metabolized narcotic analgesics (including potentially fatal respiratory depression) is recommended with co-administration.
Source: FDA drug label - darunavir, cobicistat, emtricitabine, and tenofovir alafenamide