Efavirenz%2C Emtricitabine And Tenofovir Disoproxil Fumarate + Voriconazole Interaction
Contraindicatedinteraction on record
Description
voriconazole ↓ voriconazole ↑ efavirenz Coadministration of efavirenz, emtricitabine and tenofovir disoproxil fumarate with voriconazole is contraindicated [see Contraindications ( 4 )] because it may lead to reduced therapeutic effect of voriconazole and increased risk of EFV-associated adverse reactions Anti-infective: clarithromycin ↓ clarithromycin ↑ 14-OH metabolite Consider alternatives to macrolide antibiotics because of the risk of QT interval prolongation.
Source: FDA drug label - efavirenz, emtricitabine and tenofovir disoproxil fumarate