Olmesartan Medoxomil And Amlodipine Besylate And Hydrochlorothiazide + Hydrochlorothiazide Interaction
Moderateinteraction on record
Description
• Increased exposure to cyclosporin and tacrolimus • Increased amlodipine exposure when coadministered with CYP3A inhibitors Hydrochlorothiazide ( 7.3 ): • Antidiabetic drugs: Dosage adjustment of antidiabetic may be required. Closely monitor blood pressure, renal function and electrolytes in patients on olmesartan medoxomil, amlodipine, and hydrochlorothiazide tablets and other agents that affect the RAS. Do not co-administer aliskiren with olmesartan medoxomil, amlodipine, and hydrochlorothiazide tablets in patients with diabetes [See Contraindications ( 4 )] .
Source: FDA drug label - olmesartan medoxomil and amlodipine besylate and hydrochlorothiazide