Cyproheptadine Hydrochloride has 5 known drug interactions based on U.S. FDA drug labeling data. 1 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Mao Inhibitors, Acidifying Agents, Alcohol. Patients taking Cyproheptadine Hydrochloride should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 5
- Major
- 1
- Moderate
- 4
Major (1)
- Cyproheptadine Hydrochloride + Mao Inhibitors— MAO inhibitors prolong and intensify the anticholinergic effects of cyproheptadine.
Moderate (4)
- Cyproheptadine Hydrochloride + Acidifying Agents— Antianxiety agents may have additive CNS depressant effects with cyproheptadine.
- Cyproheptadine Hydrochloride + Alcohol— Alcohol may have additive effects with cyproheptadine on CNS depression.
- Cyproheptadine Hydrochloride + Sedatives— Sedatives may have additive CNS depressant effects with cyproheptadine.
- Cyproheptadine Hydrochloride + Tranquilizers— Tranquilizers may have additive CNS depressant effects with cyproheptadine.