Thyroid has 29 known drug interactions based on U.S. FDA drug labeling data. 2 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Amitriptyline Hydrochloride, Oral Anticoagulants, Acarbose. Patients taking Thyroid should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 29
- Major
- 2
- Moderate
- 27
Major (2)
- Thyroid + Amitriptyline Hydrochloride— Serious interaction requiring monitoring; see WARNINGS section for detailed guidance.
- Thyroid + Oral Anticoagulants— Thyroid hormones increase catabolism of vitamin K-dependent clotting factors, impairing compensatory increases in clotti…
Moderate (27)
- Thyroid + Acarbose— Thyroid products produce hyperglycemia and may lead to loss of blood glucose control in patients receiving Acarbose. Clo…
- Thyroid + Alogliptin And Metformin Hydrochloride— May produce hyperglycemia and lead to loss of glycemic control.
- Thyroid + Cholestyramine Light— Cholestyramine may delay or reduce the absorption of thyroid preparations.
- Thyroid + Cholestyramine Powder For Suspension— Cholestyramine may delay or reduce the absorption of thyroid preparations.
- Thyroid + Choleystyramine Light— Cholestyramine may delay or reduce absorption of thyroid preparations.
- Thyroid + Colestipol— Colestipol binds levothyroxine and liothyronine in the intestine, impairing absorption. Four to five hours should elapse…
- Thyroid + Dapagliflozin And Metformin Hydrochloride— Produce hyperglycemia and may lead to loss of glycemic control when used with XIGDUO XR.
- Thyroid + Digoxin— Administration to a digitalized, hypothyroid patient may increase the dose requirement of digoxin.
- Thyroid + Doconexent, Niacinamide, .Alpha.-Tocopherol Acetate, Dl-, Cholecalciferol, .Beta.-Carotene, Ascorbic Acid, Thiamine Mononitrate, Riboflavin, Pyridoxine Hydrochloride, Cyanocobalamin, Iron, Zinc Oxide, Cupric Oxide, Potassium Iodide, Magnesium Oxide, Folic Acid, And Levomefolate Calcium— Anti-thyroid drugs used with iodine supplementation may lead to hypothyroidism.
- Thyroid + Empagliflozin, Metformin Hydrochloride— May produce hyperglycemia and lead to loss of glycemic control; monitor closely.
- Thyroid + Ertugliflozin And Metformin Hydrochloride— May produce hyperglycemia and lead to loss of glycemic control; close monitoring recommended.
- Thyroid + Estrogens— Estrogens increase serum thyroxine-binding globulin, decreasing free levothyroxine. Patients without functioning thyroid…
- Thyroid + Glibenclamide— Thyroid products may produce hyperglycemia and lead to loss of control of glyburide. Patients should be closely observed…
- Thyroid + Glipizide— Thyroid products may produce hyperglycemia and lead to loss of glycemic control. Patient should be observed closely for …
- Thyroid + Glipizide And Metformin Hydrochloride— Thyroid products may produce hyperglycemia and lead to loss of blood glucose control. Patient should be closely observed…
- Thyroid + Glyburide And Metformin Hydrochloride— Thyroid products tend to produce hyperglycemia and may lead to loss of blood glucose control. Close observation required…
- Thyroid + Insulin Human— Initiating thyroid replacement therapy may cause increases in insulin requirements. Patients receiving insulin should be…
- Thyroid + Linagliptin And Metformin Hydrochloride— Thyroid products may produce hyperglycemia and lead to loss of glycemic control. Close monitoring of glycemic control is…
- Thyroid + Metformin— Produce hyperglycemia and may lead to loss of glycemic control when used with metformin.
- Thyroid + Metformin Er 500 Mg— May produce hyperglycemia and lead to loss of glycemic control. Monitor patient closely for loss of blood glucose contro…
- Thyroid + Metformin Hydrochloride— Drugs that produce hyperglycemia and may lead to loss of glycemic control; monitor blood glucose.
- Thyroid + Metformin Hydrochloride Extended-Release Tablets— May produce hyperglycemia and lead to loss of glycemic control during metformin therapy; monitor blood glucose.
- Thyroid + Metformin Hydrochloride Tablet— May produce hyperglycemia and lead to loss of glycemic control when used with metformin.
- Thyroid + Nateglinide— May reduce blood-glucose-lowering effect of nateglinide and increase susceptibility to hyperglycemia. Dose increases and…
- Thyroid + Oral Contraceptives— Estrogen-containing oral contraceptives increase serum thyroxine-binding globulin, decreasing free levothyroxine. Patien…
- Thyroid + Prenatal Supplement With Dha— Anti-thyroid drugs used with iodine supplementation may lead to hypothyroidism.
- Thyroid + Sitagliptin And Metformin Hydrochloride— May produce hyperglycemia and lead to loss of glycemic control. Monitor blood glucose closely during concomitant use.