Methenamine mandelate should not be administered concurrently with sulfonamides due to insoluble precipitate formation in acid urine.
Source: NLP:methenamine mandelate
Brand names: Methenamine Mandelate
Route: Oral
Contraindications
CONTRAINDICATIONS Methenamine mandelate tablets are contraindicated in patients with renal insufficiency, severe hepatic disease, severe dehydration, and in patients who have exhibited hypersensitivity to any components of this product.
Pregnancy & Breastfeeding
Pregnancy Teratogenic Effects Pregnancy Category C Animal reproduction studies have not been conducted with methenamine mandelate. It is also not known whether methenamine mandelate can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Since methenamine is known to cross the placental barrier, methenamine mandelate should be given to a pregnant woman only if the potential benefit outweighs the risk.
3 interactions on record
Methenamine mandelate should not be administered concurrently with sulfonamides due to insoluble precipitate formation in acid urine.
Source: NLP:methenamine mandelate
Formaldehyde and sulfamethizole form an insoluble precipitate in acid urine; concurrent use should not occur.
Source: NLP:methenamine mandelate
Concurrent use may lead to increased serum salicylate levels due to reduced excretion in acidified urine.
Source: NLP:methenamine mandelate