Nephrotoxicity has been reported following concomitant administration of aminoglycoside antibiotics and cephalosporin antibiotics.
Source: NLP:cefprozil
Brand names: Cefprozil
Cephalosporin Antibacterial
Route: Oral
Contraindications
CONTRAINDICATIONS Cefprozil tablets are contraindicated in patients with known allergy to the cephalosporin class of antibiotics.
Pregnancy & Breastfeeding
Pregnancy Teratogenic Effects: Pregnancy Category B Reproduction studies have been performed in rabbits, mice, and rats using oral doses of cefprozil of 0.8, 8.5, and 18.5 times the maximum daily human dose (1000 mg) based upon mg/m 2 , and have revealed no harm to the fetus. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.
3 interactions on record
Nephrotoxicity has been reported following concomitant administration of aminoglycoside antibiotics and cephalosporin antibiotics.
Source: NLP:cefprozil
Concomitant administration of probenecid doubled the AUC for cefprozil, indicating significant pharmacokinetic interaction.
Source: NLP:cefprozil
Antacid administration 5 minutes before cefprozil capsules did not affect bioavailability.
Source: NLP:cefprozil