Cefaclor + Aluminum HydroxideModerate
Aluminum hydroxide-containing antacids diminish the extent of absorption of cefaclor extended-release tablets if taken within 1 hour of administration.
Source: NLP:cefaclor
Cefaclor Interactions
Brand names: Cefaclor
Route: Oral
Contraindications
CONTRAINDICATIONS Cefaclor extended-release tablets are contraindicated in patients with known hypersensitivity to cefaclor and other cephalosporins.
Pregnancy & Breastfeeding
Usage in Pregnancy Teratogenic Effect Reproduction studies using cefaclor have been performed in mice, rats and ferrets at doses up to 3 to 5 times the maximum human dose (1500 mg/day) based on mg/m 2 . These studies have revealed no harm to the fetus due to cefaclor. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, cefaclor extended-release tablets should be used during pregnancy only if clearly needed.
7 interactions on record
Cefaclor + LeflunomideModerate
Exposure to cefaclor may be increased when coadministered with leflunomide. Monitor and adjust dose as required.
Source: NLP:leflunomide
Exposure of cefaclor may be increased in patients taking leflunomide. Monitor and adjust dose as required.
Source: NLP:leflunomide and diclofenac sodium gel
Cefaclor + Magnesium HydroxideModerate
Magnesium hydroxide-containing antacids diminish the extent of absorption of cefaclor extended-release tablets if taken within 1 hour of administration.
Source: NLP:cefaclor
Cefaclor + ProbenecidModerate
Probenecid inhibits the renal excretion of cefaclor, potentially increasing cefaclor levels.
Source: NLP:cefaclor
Cefaclor + TeriflunomideModerate
Teriflunomide may increase exposure of cefaclor. Monitor patients and adjust dose as required.
Source: NLP:teriflunomide
Cefaclor + WarfarinModerate
Rare reports of increased prothrombin time with or without clinical bleeding in patients receiving cefaclor and warfarin concomitantly.
Source: NLP:cefaclor