Lidocaine patch 5% with mexiletine has additive and potentially synergistic toxic effects. Use with caution in patients receiving Class I antiarrhythmic drugs.
Source: NLP:lidocaine, dimethicone
Lidocaine, Dimethicone Interactions
Brand names: Dermacinrx Zrm Pak
Contraindications
CONTRAINDICATIONS Lidocaine patch 5% is contraindicated in patients with a known history of sensitivity to local anesthetics of the amide type, or to any other component of the product.
Pregnancy & Breastfeeding
Pregnancy Teratogenic Effects: Pregnancy Category B. Lidocaine patch 5% has not been studied in pregnancy. Reproduction studies with lidocaine have been performed in rats at doses up to 30 mg/kg subcutaneously and have revealed no evidence of harm to the fetus due to lidocaine. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, lidocaine patch 5% should be used during pregnancy only if clearly needed.
3 interactions on record
Lidocaine patch 5% with tocainide has additive and potentially synergistic toxic effects. Use with caution in patients receiving Class I antiarrhythmic drugs.
Source: NLP:lidocaine, dimethicone
When lidocaine patch 5% is used concomitantly with other products containing local anesthetic agents, the total amount absorbed from all formulations must be considered.
Source: NLP:lidocaine, dimethicone