Levalbuterol Hydrochloride has 7 known drug interactions based on U.S. FDA drug labeling data. Of these, 1 are contraindicated combinations that should be avoided entirely. 2 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Nonselective Beta-Adrenergic Antagonists, Epinephrine, Monoamine Oxidase Inhibitors (Maois). Patients taking Levalbuterol Hydrochloride should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 7
- Contraindicated
- 1
- Major
- 2
- Moderate
- 4
Contraindicated (1)
- Levalbuterol Hydrochloride + Nonselective Beta-Adrenergic Antagonists— May block bronchodilatory effects and produce severe bronchospasm. Patients with asthma should not normally be treated w…
Major (2)
- Levalbuterol Hydrochloride + Epinephrine— May potentiate effect and cause deleterious cardiovascular effects. Avoid concomitant use; if additional adrenergic drug…
- Levalbuterol Hydrochloride + Monoamine Oxidase Inhibitors (Maois)— Levalbuterol should be administered with extreme caution to patients on MAOIs or within 2 weeks of discontinuation due t…
Moderate (4)
- Levalbuterol Hydrochloride + Andthiazide— May worsen ECG changes or hypokalemia. Consider monitoring potassium levels during coadministration.
- Levalbuterol Hydrochloride + Digoxin— Levalbuterol may decrease serum digoxin levels by 16-22%. Monitor digoxin levels in patients receiving chronic therapy.
- Levalbuterol Hydrochloride + Diuretics— Non-potassium-sparing diuretics may have worsening ECG changes or hypokalemia when combined with beta-agonists. Monitor …
- Levalbuterol Hydrochloride + Loop Diuretics— May worsen ECG changes or hypokalemia. Consider monitoring potassium levels during coadministration.