Salicylic Acid 10% Interactions

Pregnancy & Breastfeeding

Pregnancy: Pregnancy (Category C) Salicylic acid is teratogenic in rats and monkeys. It is difficult to extrapolate from oral doses of acetylsalicylic acid used in these studies to topical administration as the oral dose to monkeys may represent four times the Maximum daily human dose of salicylic acid when applied topically over a large body surface. There are no adequate and well-controlled studies in pregnant women. Salicate™ should be used during pregnancy only if the potential benefit justifies the risk to the fetus. Nursing Mothers It is unknown whether topically applied salicylic acid is excreted in human milk. Since many drugs are excreted in human milk, caution should be exercised by physicians when administering Salicate™ to nursing mothers and nursing mothers should certainly not apply Salicate™ to the chest area or any other part of the body with which the nursing child's mouth is likely to come in contact. Because of the potential for serious adverse reactions in nursing infants from the mother's use of Salicate™ , a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Carcinogenesis, Mutagenesis, Impairment of Fertility No data are available concerning the potential carcinogenic or reproductive effects of Salicate™ . It has been shown to lack mutagenic potential in the Ames Salmonella test.