Berotralstat Hydrochloride has 2 known drug interactions based on U.S. FDA drug labeling data. 1 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with P-Gp Or Bcrp Substrates, Desogestrel. Patients taking Berotralstat Hydrochloride should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 2
- Major
- 1
- Moderate
- 1
Major (1)
- Berotralstat Hydrochloride + P-Gp Or Bcrp Substrates— P-gp inducers may decrease berotralstat plasma concentration, leading to reduced efficacy of ORLADEYO. Avoid concomitant…
Moderate (1)
- Berotralstat Hydrochloride + Desogestrel— Concomitant use increases exposure to etonogestrel (active metabolite of desogestrel) and may increase risk of desogestr…