Estradiol Gel 0.1% has 10 known drug interactions based on U.S. FDA drug labeling data. Notable interactions include combinations with Carbamazepine, Clarithromycin, Erythromycin. Patients taking Estradiol Gel 0.1% should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 10
- Moderate
- 10
Moderate (10)
- Estradiol Gel 0.1% + Carbamazepine— CYP3A4 inducer that may reduce estradiol plasma concentrations, possibly decreasing therapeutic effects and altering ute…
- Estradiol Gel 0.1% + Clarithromycin— CYP3A4 inhibitor that may increase estradiol plasma concentrations and result in adverse reactions.
- Estradiol Gel 0.1% + Erythromycin— CYP3A4 inhibitor that may increase estradiol plasma concentrations and result in adverse reactions.
- Estradiol Gel 0.1% + Grapefruit Juice— CYP3A4 inhibitor that may increase estradiol plasma concentrations and result in adverse reactions.
- Estradiol Gel 0.1% + Itraconazole— CYP3A4 inhibitor that may increase estradiol plasma concentrations and result in adverse reactions.
- Estradiol Gel 0.1% + Ketoconazole— CYP3A4 inhibitor that may increase estradiol plasma concentrations and result in adverse reactions.
- Estradiol Gel 0.1% + Phenobarbital— CYP3A4 inducer that may reduce estradiol plasma concentrations, possibly decreasing therapeutic effects and altering ute…
- Estradiol Gel 0.1% + Rifampin— CYP3A4 inducer that may reduce estradiol plasma concentrations, possibly decreasing therapeutic effects and altering ute…
- Estradiol Gel 0.1% + Ritonavir— CYP3A4 inhibitor that may increase estradiol plasma concentrations and result in adverse reactions.
- Estradiol Gel 0.1% + St. John'S Wort— CYP3A4 inducer that may reduce estradiol plasma concentrations, possibly decreasing therapeutic effects and altering ute…