Concurrent use increases risk of severe and potentially fatal hyperkalemia, particularly with other hyperkalemia risk factors.
Source: NLP:potassium chloride and dextrose monohydrate
Potassium Chloride, Dextrose Monohydrate And Sodium Chloride Interactions
Brand names: Potassium Chloride In Dextrose And Sodium Chloride
Route: Intravenous
Contraindications
4 CONTRAINDICATIONS Potassium Chloride in Dextrose and Sodium Chloride Injection is contraindicated in patients with: • known hypersensitivity to potassium chloride, dextrose and/or sodium chloride [see Warnings and Precautions 5.1) ] • clinically significant hyperkalemia [see Warnings and Precautions (5.2) ] • clinically significant hyperglycemia [see Warnings and Precautions (5.3) ] • Known hypersensitivity to potassium chloride, dextrose, or sodium chloride ( 4 , 5.1 ) • Clinically significant hyperkalemia ( 4 , 5.2 ) • Clinically significant hyperglycemia ( 4 , 5.3 )
Pregnancy & Breastfeeding
8.1 Pregnancy Risk Summary Appropriate administration of Potassium Chloride in Dextrose Sodium Chloride Injection during pregnancy is not expected to cause adverse developmental outcomes, including congenital malformations. Animal reproduction studies have not been conducted with Potassium Chloride in Dextrose Sodium Chloride Injection. The estimated background risk of major birth defects and miscarriage for the indicated population is unknown. All pregnancies have a background risk of birth defect, loss, or other adverse outcomes. In the U.S. general population, the estimated background risk of major birth defects and miscarriage in clinically recognized pregnancies is 2 to 4% and 15 to 20%, respectively.
3 interactions on record
Concurrent use increases risk of severe and potentially fatal hyperkalemia, particularly with other hyperkalemia risk factors.
Source: NLP:potassium chloride and dextrose monohydrate
Renal sodium and lithium clearance may be increased, resulting in decreased serum lithium concentrations. Monitor serum lithium concentrations during concomitant use.
Source: NLP:dextrose monohydrate, sodium chloride