Doxylamine Succinate And Pyridoxine Hydrochloride has 5 known drug interactions based on U.S. FDA drug labeling data. Of these, 1 are contraindicated combinations that should be avoided entirely. 4 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Monoamine Oxidase Inhibitors (Maois), Alcohol, Cns Depressants. Patients taking Doxylamine Succinate And Pyridoxine Hydrochloride should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 5
- Contraindicated
- 1
- Major
- 4
Contraindicated (1)
- Doxylamine Succinate And Pyridoxine Hydrochloride + Monoamine Oxidase Inhibitors (Maois)— Use is contraindicated; MAOIs prolong and intensify the anticholinergic (drying) effects of antihistamines.
Major (4)
- Doxylamine Succinate And Pyridoxine Hydrochloride + Alcohol— Concurrent use not recommended; severe drowsiness can occur when combined with alcohol or other sedating medications.
- Doxylamine Succinate And Pyridoxine Hydrochloride + Cns Depressants— Concurrent use not recommended; severe drowsiness can occur. Includes hypnotic sedatives and tranquilizers.
- Doxylamine Succinate And Pyridoxine Hydrochloride + Hypnotic Medications— Concurrent use is not recommended; severe drowsiness can occur with CNS depressants.
- Doxylamine Succinate And Pyridoxine Hydrochloride + Tranquilizers— Concurrent use is not recommended; severe drowsiness can occur with CNS depressants.