Vorasidenib has 4 known drug interactions based on U.S. FDA drug labeling data. 4 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Cyp3a Inducers, Mao Inhibitors, Oral Contraceptives. Patients taking Vorasidenib should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 4
- Major
- 4
Major (4)
- Vorasidenib + Cyp3a Inducers— Concomitant use may decrease vorasidenib plasma concentrations and reduce anti-tumor activity.
- Vorasidenib + Mao Inhibitors— Concomitant use may increase vorasidenib plasma concentrations and increase risk of adverse reactions.
- Vorasidenib + Oral Contraceptives— Concomitant use may decrease hormonal contraceptive concentrations, leading to contraception failure and breakthrough bl…
- Vorasidenib + Tobacco Smoke— Smoking tobacco with moderate CYP1A2 inducers may decrease vorasidenib plasma concentrations and reduce anti-tumor activ…