Dordaviprone has 3 known drug interactions based on U.S. FDA drug labeling data. 3 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Cyp3a Inducers, Drugs Known To Induce Hyperkalemia, Mao Inhibitors. Patients taking Dordaviprone should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 3
- Major
- 3
Major (3)
- Dordaviprone + Cyp3a Inducers— Strong CYP3A4 inducers decrease dordaviprone exposure, which may reduce the anti-tumor activity of MODEYSO. Avoid concom…
- Dordaviprone + Drugs Known To Induce Hyperkalemia— Concomitant use may increase the risk of QTc-associated arrhythmias. Avoid concomitant use or separate administration if…
- Dordaviprone + Mao Inhibitors— Strong CYP3A4 inhibitors increase dordaviprone exposure, which may increase the risk of MODEYSO-related adverse reaction…