Dipyridamole Interactions

Brand names: Dipyridamole

Platelet Aggregation Inhibitor

Route: Intravenous

Contraindications

CONTRAINDICATIONS Hypersensitivity to dipyridamole.

Pregnancy & Breastfeeding

Pregnancy Teratogenic Effects – Pregnancy Category B Reproduction studies performed in mice and rats at daily oral doses of up to 125 mg/kg (15.6 times* the maximum recommended daily human oral dose) and in rabbits at daily oral doses of up to 20 mg/kg (2.5 times* the maximum recommended daily human oral dose) have revealed no evidence of impaired embryonic development due to dipyridamole. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human responses, this drug should be used during pregnancy only if clearly needed. * Calculation based on assumed body weight of 50 kg.

9 interactions on record

Co-administration with dipyridamole is contraindicated because of hypotension.

Source: NLP:riociguat

Dipyridamole increases plasma levels and cardiovascular effects of adenosine. Adjustment of adenosine dosage may be necessary.

Source: NLP:dipyridamole

Potent BCRP, ENT1, and CNT3 transporter inhibitor may alter cladribine bioavailability, intracellular distribution, and renal elimination.

Source: NLP:cladribine

Platelet inhibitor that may enhance risk of hemorrhage. Discontinue prior to Lovenox initiation if possible, or conduct close clinical and laboratory monitoring if coadministration is essential.

Source: NLP:enoxaparin sodium

Dipyridamole increases cardiovascular effects of regadenoson (adenosine A2A-receptor agonist). Risk of cardiovascular side effects may be increased during stress testing.

Source: NLP:dipyridamole

Interferes with platelet aggregation and may induce bleeding. Use with caution; dose reduction of antiplatelet agent or heparin recommended.

Source: NLP:heparin sodium

Dipyridamole may counteract anticholinesterase effect of cholinesterase inhibitors, potentially aggravating myasthenia gravis.

Source: NLP:dipyridamole

Drug interaction mentioned but description incomplete in provided text.

Source: NLP:metoprolol

Beta-blocker administration should be withheld before use (interaction mentioned but details incomplete).

Source: NLP:metoprolol tartrate