Combination of cromolyn sodium and isoproterenol in pregnant mice increased incidence of resorptions and malformations compared to isoproterenol alone.
Source: NLP:cromolyn sodium
Cromolyn Sodium Interactions
Brand names: Cromolyn Sodium
Route: Oral
Contraindications
CONTRAINDICATIONS Cromolyn Sodium, USP is contraindicated in those patients who have shown hypersensitivity to cromolyn sodium.
Pregnancy & Breastfeeding
Pregnancy In reproductive studies in pregnant mice, rats, and rabbits, cromolyn sodium produced no evidence of fetal malformations at subcutaneous doses up to 540 mg/kg in mice (approximately equal to the maximum recommended daily oral dose in adults on a mg/m 2 basis) and 164 mg/kg in rats (less than the maximum recommended daily oral dose in adults on a mg/m 2 basis) or at intravenous doses up to 485 mg/kg in rabbits (approximately 4 times the maximum recommended daily oral dose in adults on a mg/m 2 basis). There are, however, no adequate and well controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.
1 interaction on record