ACE inhibitors may increase serum potassium levels when used with potassium chloride, potentially leading to hyperkalemia.
Source: NLP:potassium chloride extended-release
Brand names: Potassium Chloride
Route: Oral
Contraindications
CONTRAINDICATIONS Potassium supplements are contraindicated in patients with hyperkalemia since a further increase in serum potassium concentration in such patients can produce cardiac arrest. Hyperkalemia may complicate any of the following conditions: chronic renal failure, systemic acidosis, such as diabetic acidosis, acute dehydration, extensive tissue breakdown as in severe burns, adrenal insufficiency, or the administration of a potassium-sparing diuretic (eg, spironolactone, triamterene, amiloride) (see OVERDOSAGE ). Controlled-release formulations of potassium chloride have produced esophageal ulceration in certain cardiac patients with esophageal compression due to enlarged left atrium. Potassium supplementation, when indicated in such patients, should be given as a liquid preparation or as an aqueous (water) suspension of potassium chloride (see PRECAUTIONS: Information for Patients , and DOSAGE AND ADMINISTRATION sections). All solid oral dosage forms of potassium chloride are contraindicated in any patient in whom there is structural, pathological (eg, diabetic gastroparesis), or pharmacologic (use of anticholinergic agents or other agents with anticholinergic properties at sufficient doses to exert anticholinergic effects) cause for arrest or delay in tablet passage through the gastrointestinal tract.
Pregnancy & Breastfeeding
Pregnancy Animal reproduction studies have not been conducted with potassium chloride. It is unlikely that potassium supplementation that does not lead to hyperkalemia would have an adverse effect on the fetus or would affect reproductive capacity.
2 interactions on record
ACE inhibitors may increase serum potassium levels when used with potassium chloride, potentially leading to hyperkalemia.
Source: NLP:potassium chloride extended-release
Potassium-sparing diuretics may increase serum potassium levels when used with potassium chloride, potentially leading to hyperkalemia.
Source: NLP:potassium chloride extended-release