Vinorelbine has 5 known drug interactions based on U.S. FDA drug labeling data. Notable interactions include combinations with Aprepitant, Fosaprepitant, Fosaprepitant Dimeglumine. Patients taking Vinorelbine should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 5
- Moderate
- 5
Moderate (5)
- Vinorelbine + Aprepitant— Increased vinorelbine exposure possible; no dosage adjustment needed but monitor for adverse reactions.
- Vinorelbine + Fosaprepitant— Increased exposure of chemotherapeutic agent; no dosage adjustment needed but monitor for adverse effects.
- Vinorelbine + Fosaprepitant Dimeglumine— Increased exposure possible via CYP3A4 inhibition, but no dosage adjustment needed. Monitor for adverse reactions.
- Vinorelbine + Mao Inhibitors— Concurrent administration may cause earlier onset and/or increased severity of adverse reactions. Exercise caution in pa…
- Vinorelbine + Netupitant And Palonosetron— Chemotherapy agent metabolized by CYP3A4; systemic exposure can increase with AKYNZEO; caution and monitoring advised.