Concomitant use may contribute to the risk of intestinal necrosis and is not recommended.
Source: NLP:sodium polystyrene sulfonate
Sodium Polystyrene Sulfonate Interactions
Brand names: Sodium Polystyrene Sulfonate
Potassium Binder · Potassium Ion Exchange Activity
Route: Oral, Rectal
Contraindications
CONTRAINDICATIONS SPS ® Suspension is contraindicated in the following conditions: patients with hypokalemia, patients with a history of hypersensitivity to polystyrene sulfonate resins, obstructive bowel disease, oral or rectal administration in neonates (See PRECAUTIONS ).
Pregnancy & Breastfeeding
Pregnancy Category C Animal reproduction studies have not been conducted with sodium polystyrene sulfonate. It is also not known whether sodium polystyrene sulfonate can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Sodium polystyrene sulfonate should be given to a pregnant woman only if clearly needed.
5 interactions on record
Simultaneous administration may reduce the resin's potassium exchange capability and increase risk of systemic alkalosis.
Source: NLP:sodium polystyrene sulfonate
Sodium Polystyrene Sulfonate may bind thyroxine and decrease its gastrointestinal absorption. Administer at least 3 hours before or after Sodium Polystyrene Sulfonate.
Source: NLP:sodium polystyrene sulfonate
Sodium Polystyrene Sulfonate may bind lithium and decrease its gastrointestinal absorption. Administer at least 3 hours before or after Sodium Polystyrene Sulfonate.
Source: NLP:sodium polystyrene sulfonate
Exchange resins reduce serum potassium levels by sodium replacement of potassium; fluid retention may occur.
Source: NLP:triamterene and hydrochlorothiazide