Home›Dapsone Gel, 5%

Dapsone Gel, 5%

Also known as: Dapsone

Sulfone

Route: Topical

22 interactions on record

Dapsone Gel, 5% has 22 known drug interactions based on U.S. FDA drug labeling data. 14 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Acetaminophen, Acetanilide, Acetazolamide. Patients taking Dapsone Gel, 5% should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.

Total: 22
Major: 14
Moderate: 5
Minor: 2

Major (14)

Dapsone Gel, 5% + Acetaminophen— Concomitant use may increase risk of developing methemoglobinemia. Monitor closely.
Dapsone Gel, 5% + Acetanilide— Concomitant use may increase risk of developing methemoglobinemia. Monitor closely.
Dapsone Gel, 5% + Acetazolamide— Concomitant use may increase risk of developing methemoglobinemia. Monitor closely.
Dapsone Gel, 5% + Benzocaine— Concomitant use may increase risk of developing methemoglobinemia. Monitor closely.
Dapsone Gel, 5% + Chloroquine— Concomitant use may increase risk of developing methemoglobinemia. Monitor closely.
Dapsone Gel, 5% + Nitrofurantoin— Concomitant use may increase risk of developing methemoglobinemia. Monitor closely.
Dapsone Gel, 5% + Nitroglycerin— Concomitant use may increase risk of developing methemoglobinemia. Monitor closely.
Dapsone Gel, 5% + Nitroprusside— Concomitant use may increase risk of developing methemoglobinemia. Monitor closely.
Dapsone Gel, 5% + Para-Aminosalicylic Acid— Concomitant use may increase risk of developing methemoglobinemia. Monitor closely.
Dapsone Gel, 5% + Phenacetin— Concomitant use may increase risk of developing methemoglobinemia. Monitor closely.
Dapsone Gel, 5% + Phenobarbital— Concomitant use may increase risk of developing methemoglobinemia. Monitor closely.
Dapsone Gel, 5% + Phenytoin— Concomitant use may increase risk of developing methemoglobinemia. Monitor closely.
Dapsone Gel, 5% + Primaquine— Concomitant use may increase risk of developing methemoglobinemia. Monitor closely.
Dapsone Gel, 5% + Quinine— Concomitant use may increase risk of developing methemoglobinemia. Monitor closely.

Moderate (5)

Dapsone Gel, 5% + Oral Anticoagulants— May increase formation of dapsone hydroxylamine, a metabolite associated with hemolysis.
Dapsone Gel, 5% + Pyrimethamine— Folic acid antagonist that may increase the likelihood of hematologic reactions when used with dapsone.
Dapsone Gel, 5% + Rifampin— May increase formation of dapsone hydroxylamine, a metabolite associated with hemolysis.
Dapsone Gel, 5% + St. John'S Wort— May increase formation of dapsone hydroxylamine, a metabolite associated with hemolysis.
Dapsone Gel, 5% + Sulfamethoxazole And Trimethoprim— TMP/SMX increases systemic levels of dapsone and its metabolites by approximately 40% for dapsone, 20% for N-acetyl-daps…