Combined use with other anorectic agents is contraindicated due to potential for serious cardiac problems.
Source: NLP:diethylpropion hydrochloride
Brand names: Diethylpropion Hydrochloride
Route: Oral
Contraindications
CONTRAINDICATIONS Pulmonary hypertension, advanced arteriosclerosis, hyperthyroidism, known hypersensitivity or idiosyncrasy to the sympathomimetic amines, glaucoma, severe hypertension. (See PRECAUTIONS .) Agitated states. Patients with a history of drug abuse. Use in combination with other anorectic agents is contraindicated. During or within 14 days following the administration of monoamine oxidase inhibitors, hypertensive crises may result.
Pregnancy & Breastfeeding
Pregnancy Teratogenic Effects: Pregnancy Category B. Reproduction studies have been performed in rats at doses up to 1.6 times the human dose (based on mg/m 2 ) and have revealed no evidence of impaired fertility or harm to the fetus due to diethylpropion hydrochloride. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Spontaneous reports of congenital malformations have been recorded in humans, but no causal relationship to diethylpropion has been established. Nonteratogenic Effects. Abuse with diethylpropion hydrochloride during pregnancy may result in withdrawal symptoms in the human neonate.
9 interactions on record
Combined use with other anorectic agents is contraindicated due to potential for serious cardiac problems.
Source: NLP:diethylpropion hydrochloride
Hypertension may result when diethylpropion is used with MAO inhibitors due to monoamine interaction.
Source: NLP:diethylpropion hydrochloride
Combined use may have potential for serious cardiac problems; efficacy has not been studied.
Source: NLP:diethylpropion hydrochloride
Concurrent use may result in arrhythmias.
Source: NLP:diethylpropion hydrochloride
Diethylpropion may interfere with antihypertensive effects; pressor effects may be additive.
Source: NLP:diethylpropion hydrochloride
Pressor effects are additive; diethylpropion may interfere with antihypertensive efficacy.
Source: NLP:diethylpropion hydrochloride
Antidiabetic drug requirements may be altered when used concurrently with diethylpropion.
Source: NLP:diethylpropion hydrochloride
Diethylpropion may interfere with antihypertensive effects of α-methyldopa.
Source: NLP:diethylpropion hydrochloride
Concurrent use may antagonize the anorectic effect of diethylpropion.
Source: NLP:diethylpropion hydrochloride