Caution must be exercised when administering 0.45% Sodium chloride injection to patients receiving corticosteroids due to potential interaction.
Source: NLP:sodium chloride
Sodium Chloride Interactions
Brand names: Sodium Chloride
Route: Intravenous
FDA Black Box Warning
WARNING: NOT FOR USE IN NEONATES.
Contraindications
CONTRAINDICATIONS None known.
Pregnancy & Breastfeeding
Pregnancy: Teratogenic Effects Pregnancy Category C Animal reproduction studies have not been conducted with Sodium Chloride Injection, USP. It is also not known whether Sodium Chloride Injection, USP can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Sodium Chloride Injection, USP should be given to a pregnant woman only if clearly needed.
4 interactions on record
Sodium Chloride + DiureticsModerate
Diuretics are associated with hyponatremia; concomitant use with 0.9% sodium chloride injection may increase risk of developing hyponatremia.
Source: NLP:sodium chloride
Sodium Chloride + LithiumModerate
Renal sodium and lithium clearance may be altered during sodium chloride injection administration, potentially resulting in increased or decreased lithium concentrations.
Source: NLP:sodium chloride
Caution must be exercised when administering 0.45% Sodium chloride injection to patients receiving corticotropin due to potential interaction.
Source: NLP:sodium chloride