Acetazolamide Sodium + Sulphonamide Interaction
Moderateinteraction on record
Description
Acetazolamide modifies phenytoin metabolism with increased serum levels of phenytoin. By decreasing the gastrointestinal absorption of primidone, acetazolamide may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. Caution is advised when beginning, discontinuing, or changing the dose of acetazolamide in patients receiving primidone.
Source: FDA drug label - acetazolamide sodium