Acetazolamide Sodium has 13 known drug interactions based on U.S. FDA drug labeling data. Notable interactions include combinations with Acetazolamide, Acidifying Agents, Amphetamine. Patients taking Acetazolamide Sodium should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 13
- Moderate
- 12
Moderate (12)
- Acetazolamide Sodium + Acetazolamide— Acetazolamide modifies phenytoin metabolism with increased serum levels of phenytoin. By decreasing the gastrointestinal…
- Acetazolamide Sodium + Acidifying Agents— Acetazolamide may increase or decrease blood glucose levels; consideration should be taken in patients on antidiabetic t…
- Acetazolamide Sodium + Amphetamine— Acetazolamide decreases urinary excretion of amphetamine and may enhance magnitude and duration of its effect.
- Acetazolamide Sodium + Cyclosporine— Acetazolamide may elevate cyclosporine levels.
- Acetazolamide Sodium + Folic Acid— Acetazolamide may increase the effects of other folic acid antagonists.
- Acetazolamide Sodium + Lithium— Acetazolamide increases lithium excretion, which may decrease lithium levels.
- Acetazolamide Sodium + Mao Inhibitors— Concomitant use not advisable due to possible additive effects.
- Acetazolamide Sodium + Methenamine Salts— Acetazolamide may prevent the urinary antiseptic effect of methenamine.
- Acetazolamide Sodium + Phenytoin— Acetazolamide modifies phenytoin metabolism with increased serum levels, which may increase osteomalacia occurrence in c…
- Acetazolamide Sodium + Primidone— Acetazolamide decreases gastrointestinal absorption of primidone, potentially decreasing serum concentrations and antico…
- Acetazolamide Sodium + Quinidine— Acetazolamide reduces urinary excretion of quinidine and may enhance its effect.
- Acetazolamide Sodium + Sodium Bicarbonate— Concurrent use with acetazolamide increases the risk of renal calculus formation.