Antacids Containing Calcium + Moxifloxacin Hydrochloride Tablets%2C 400 Mg Interaction

Moderateinteraction on record

Description

Multivalent cations in antacids form chelates with moxifloxacin, substantially decreasing absorption. Take moxifloxacin at least 4 hours before or 8 hours after antacids.

Mechanism

Chelation with multivalent cations reduces absorption

Source: NLP:moxifloxacin hydrochloride tablets, 400 mg