Anticoagulants (Prothrombin Depressing) + Phytonadione Interaction
Majorinteraction on record
Description
Phytonadione may induce temporary resistance to prothrombin-depressing anticoagulants, especially at larger doses, potentially requiring higher anticoagulant doses or therapy change.
Mechanism
Induction of temporary resistance to prothrombin-depressing effect
Source: NLP:phytonadione