Monoamine Oxidase Inhibitors (Maois) + Methylphenidate Interaction
Contraindicatedinteraction on record
Description
Concomitant use can cause hypertensive crisis with potentially fatal outcomes including death, stroke, myocardial infarction, and aortic dissection. Contraindicated within 14 days of MAOI discontinuation.
Mechanism
Interaction between CNS stimulant and monoamine oxidase inhibition
Source: NLP:methylphenidate