Nonsteroidal Anti Inflammatory Drugs (Nsaids) + Irbesartan Interaction

Majorinteraction on record

Description

Increased risk of renal impairment and acute renal failure, especially in elderly or volume-depleted patients. Reduced antihypertensive effects. Monitor renal function periodically.

Mechanism

NSAIDs may deteriorate renal function when combined with angiotensin II receptor antagonists

Source: NLP:irbesartan