Nonsteroidal Anti Inflammatory Drugs (Nsaids) + Lisinopril And Hydrochlorothiazide Tablets Interaction
Majorinteraction on record
Description
Co-administration may result in deterioration of renal function, including possible acute renal failure, especially in elderly patients, those volume-depleted, or with compromised renal function. NSAIDs may also attenuate the antihypertensive effect.
Mechanism
Renal function deterioration and reduced antihypertensive efficacy
Source: NLP:lisinopril and hydrochlorothiazide tablets