Nonsteroidal Anti Inflammatory Drugs (Nsaids) + Telmisartan And Hydrochlorothiazide Interaction
Majorinteraction on record
Description
NSAIDs may result in deterioration of renal function, including possible acute renal failure, and may attenuate the antihypertensive effect of ARBs. NSAIDs reduce diuretic, natriuretic, and antihypertensive effects.
Mechanism
NSAIDs antagonize effects of ARBs and diuretics; renal impairment risk in elderly, volume-depleted, or renally compromised patients
Source: NLP:telmisartan and hydrochlorothiazide