Phenobarbital%2C Hyoscyamine Sulfate%2C Atropine Sulfate%2C Scopol + Oral Anticoagulants Interaction
Moderateinteraction on record
Description
Phenobarbital may decrease the effect of anticoagulants, necessitating larger doses for optimal effect. Dose adjustment may be needed when phenobarbital is discontinued.
Mechanism
Phenobarbital-induced metabolism of anticoagulants
Source: NLP:phenobarbital, hyoscyamine sulfate, atropine sulfate, scopolamine hydrobromide