Relugolix%2C Estradiol Hemihydrate%2C And Norethindrone Acetate + Strong Cyp3a4 And P Glycoprotein Inducers Interaction
Majorinteraction on record
Description
Decreases AUC and Cmax of relugolix, estradiol, and/or norethindrone, may decrease therapeutic effects of MYFEMBREE. Avoid use.
Mechanism
P-glycoprotein and CYP3A induction
Source: NLP:relugolix, estradiol hemihydrate, and norethindrone acetate