Selective Serotonin Reuptake Inhibitors (Ssri) + Celecoxib Interaction

Moderateinteraction on record

Description

Concomitant use potentiates bleeding risk more than NSAID alone by affecting platelet serotonin release. Monitor for signs of bleeding.

Mechanism

Serotonin reuptake inhibition potentiates platelet dysfunction

Source: NLP:celecoxib