St. John'S Wort + Desogestrel And Ethinyl Estradiol And Ethinyl Estradiol Interaction

Moderateinteraction on record

Description

Induces CYP3A4 and may decrease plasma concentrations of desogestrel and ethinyl estradiol, potentially diminishing contraceptive effectiveness and increasing breakthrough bleeding.

Mechanism

CYP3A4 enzyme induction

Source: NLP:desogestrel and ethinyl estradiol