St. John'S Wort + Elexacaftor%2C Tezacaftor%2C And Ivacaftor Interaction

Contraindicatedinteraction on record

Description

Strong CYP3A inducer (Hypericum perforatum) expected to decrease TRIKAFTA component exposures and reduce efficacy.

Mechanism

CYP3A induction

Source: NLP:elexacaftor, tezacaftor, and ivacaftor