St. John'S Wort + Irinotecan Hydrochloride Interaction

Contraindicatedinteraction on record

Description

Strong CYP3A4 inducer substantially reduces exposure to irinotecan and SN-38. Do not administer unless no therapeutic alternatives exist.

Mechanism

CYP3A4 enzyme induction

Source: NLP:irinotecan hydrochloride

Related drug profiles

All St. John'S Wort interactions →All Irinotecan Hydrochloride interactions →
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