About CheckDrugInteractions.com

Why We Built This

Drug interactions are a leading cause of adverse drug events in the United States. The FDA estimates that drug interactions account for approximately 3–5% of all in-hospital medication errors — most of which are preventable if patients have easy access to interaction information before combining medications.

Existing drug interaction checkers are often buried behind paywalls, cluttered with ads, or require account creation. We built CheckDrugInteractions.com to be free, fast, and based on the same authoritative FDA data used by healthcare professionals. Check up to 20 drugs at once — including camera scanning of pill bottle labels.

Our Data

Every interaction on this site is extracted from FDA-approved drug labeling data available through OpenFDA and DailyMed. We do not invent or infer interactions — every pair listed on this site is explicitly documented in FDA drug labeling.

Our database currently indexes over 257,000 FDA drug labels and covers 22,000+ unique drug-pair interactions with severity classifications. For details on how we process this data, see our Methodology page.

Editorial Standards & Accountability

CheckDrugInteractions.com is an independent, U.S.-based project maintained by our editorial team. We hold ourselves to a single, verifiable standard: every interaction we display is reproduced directly from official FDA drug labeling — we do not add clinical opinion, re-interpret dosing, or generate interactions with AI. Each severity label traces back to the wording in the source label, and each page cites the specific FDA label it came from.

Because our data mirrors FDA labeling, it is only as current and as complete as the labels themselves — an absence of a documented interaction is never a guarantee of safety. We correct errors promptly: if you believe a page is inaccurate or out of date, email support@checkdruginteractions.com and we will review it against the current FDA label. This site does not replace the judgment of a licensed pharmacist or physician, who can account for your full history.

Limitations

This tool is for informational purposes only and is not a substitute for professional medical advice. Our database covers FDA-labeled prescription drugs and may not include all over-the-counter products, supplements, or herbal remedies. Always consult your doctor or pharmacist before making changes to your medication regimen.

Contact

For questions, corrections, or feedback, contact us at support@checkdruginteractions.com.