aspirin and dichlorphenamide: what the product label says

The product label for dichlorphenamide names aspirin in its drug-interaction information. The complete selected section is reproduced below so that qualifications stay with the finding.

Which products this evidence covers

Dichlorphenamide — TABLET — ORAL

Labeled active ingredients: DICHLORPHENAMIDE. Routes: ORAL. Dosage forms: TABLET.

Supporting label passage

Section: 7.1 Aspirin and Other Salicylates

Carbonic anhydrase inhibitors, including dichlorphenamide, can cause metabolic acidosis [see Warnings and Precautions ( 5.2 , 5.4 )] , which can increase the risk of salicylate toxicity. Anorexia, tachypnea, lethargy, and coma have been reported with concomitant use of dichlorphenamide and high-dose aspirin. Therefore, concomitant use of dichlorphenamide and high-dose aspirin is contraindicated. Patients with concomitant use of dichlorphenamide and low-dose aspirin should be carefully monitored [see Contraindications ( 4 ) and Warnings and Precautions ( 5.2 )].

Read the full product label on DailyMed. Label version 1, dated 2025-11-25.

Limits of this evidence

This passage applies to the labeled product and circumstances it describes. It must not be generalized to other routes or formulations. It does not independently validate CDI’s severity category, establish safety for an individual, or replace the full label. The stored interaction description and classification have not been changed by this article.

How this brief was prepared

Automatic checks matched drug identities, retrieved and preserved the label, and checked the full quoted section with AI assistance on 2026-11-09. The public explanation uses a fixed template; model-written medical advice is not published. Independent clinical review has not been recorded.

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