Blood concentrations of dialyzable drugs may be reduced by dialysis, requiring dosage adjustment of concomitant medications.
Source: NLP:sodium chloride, sodium lactate, calcium chloride, magnesium chloride and dextrose
Brand names: Dianeal Low Calcium With Dextrose, Dianeal Pd-2 With Dextrose
Route: Intraperitoneal
Contraindications
4 CONTRAINDICATIONS DIANEAL peritoneal dialysis solutions are contraindicated in patients with severe lactic acidosis. • Pre-existing severe lactic acidosis ( 4 )
Pregnancy & Breastfeeding
8.1 Pregnancy DIANEAL peritoneal dialysis solution is a pharmacologically inactive solution. While there are no adequate and well controlled studies in pregnant women, appropriate administration of DIANEAL solutions, with appropriate monitoring of hematology, electrolytes, blood chemistry and fluid status is not expected to cause fetal harm. Animal reproduction studies have not been conducted with DIANEAL solutions. The estimated background risk of major birth defects and miscarriage for the indicated population is unknown. In the U.S. general population, the estimated background risk of major birth defects and miscarriage in clinically recognized pregnancies is 2-4% and 15-20%, respectively.
2 interactions on record
Blood concentrations of dialyzable drugs may be reduced by dialysis, requiring dosage adjustment of concomitant medications.
Source: NLP:sodium chloride, sodium lactate, calcium chloride, magnesium chloride and dextrose
Diabetic patients may require dosage adjustments of insulin due to dialysis effects on blood glucose control.
Source: NLP:sodium chloride, sodium lactate, calcium chloride, magnesium chloride and dextrose