Lurasidone has 3 known drug interactions based on U.S. FDA drug labeling data. Of these, 2 are contraindicated combinations that should be avoided entirely. Notable interactions include combinations with Itraconazole, Ketoconazole, Deferasirox. Patients taking Lurasidone should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 3
- Contraindicated
- 2
- Moderate
- 1
Contraindicated (2)
- Lurasidone + Itraconazole— Coadministration is contraindicated. Itraconazole increases plasma concentrations, potentially increasing pharmacologic …
- Lurasidone + Ketoconazole— Ketoconazole increases lurasidone exposure and may result in serious adverse reactions.
Moderate (1)
- Lurasidone + Deferasirox— Deferasirox may induce CYP3A4 resulting in decreased lurasidone concentration. Monitor for reduced effectiveness.