Tesamorelin has 7 known drug interactions based on U.S. FDA drug labeling data. Notable interactions include combinations with Corticosteroids, Cortisone Acetate, Cyclosporine. Patients taking Tesamorelin should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 7
- Moderate
- 6
- Minor
- 1
Moderate (6)
- Tesamorelin + Corticosteroids— GH may alter clearance of corticosteroids metabolized by CYP450 liver enzymes; monitor for potential interactions.
- Tesamorelin + Cortisone Acetate— May require dose adjustment as conversion to active metabolite is dependent on 11βHSD-1 activity, which is inhibited by …
- Tesamorelin + Cyclosporine— GH may alter clearance of cyclosporine metabolized by CYP450 liver enzymes; monitor for potential interactions.
- Tesamorelin + Oral Anticoagulants— GH may alter clearance of anticonvulsants metabolized by CYP450 liver enzymes; monitor for potential interactions.
- Tesamorelin + Prednisone— May require dose adjustment as conversion to active metabolite is dependent on 11βHSD-1 activity, which is inhibited by …
- Tesamorelin + Topical Steroids— GH may alter clearance of sex steroids metabolized by CYP450 liver enzymes; monitor for potential interactions.
Minor (1)
- Tesamorelin + Simvastatin— Co-administration with tesamorelin had no significant impact on simvastatin pharmacokinetics in healthy subjects.