Tubocurarine has 23 known drug interactions based on U.S. FDA drug labeling data. 5 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Colistimethate, Colistimethate Sodium, Gentamicin Sulfate. Patients taking Tubocurarine should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 23
- Major
- 5
- Moderate
- 17
Major (5)
- Tubocurarine + Colistimethate— Curariform muscle relaxant that potentiates neuromuscular blocking effect; use with extreme caution in patients treated …
- Tubocurarine + Colistimethate Sodium— Curariform muscle relaxant that potentiates neuromuscular blocking effect; should be used with extreme caution.
- Tubocurarine + Gentamicin Sulfate— Neuromuscular blockade and respiratory paralysis possible. Use with caution in patients receiving aminoglycosides by any…
- Tubocurarine + Metolazone— Diuretic-induced hypokalemia may enhance neuromuscular blocking effects, potentially causing respiratory depression or a…
- Tubocurarine + Vecuronium Bromide— D-tubocurarine and vecuronium may manifest additive neuromuscular blocking effects when used together due to similar mec…
Moderate (17)
- Tubocurarine + Amiloride Hydrochloride And Hydrochlorothiazide— Possible increased responsiveness to nondepolarizing skeletal muscle relaxants when used with hydrochlorothiazide.
- Tubocurarine + Amphotericin B— Amphotericin B-induced hypokalemia may enhance the curariform effect of skeletal muscle relaxants. Serum potassium level…
- Tubocurarine + Amphotericin B Liposome— Amphotericin B-induced hypokalemia may enhance curariform effect of skeletal muscle relaxants. Serum potassium levels sh…
- Tubocurarine + Atenolol And Chlorthalidone— Thiazides may increase responsiveness to tubocurarine.
- Tubocurarine + Chlorothiazide— Possible increased responsiveness to tubocurarine may occur when used concurrently with chlorothiazide.
- Tubocurarine + Chlorothiazide Sodium— Possible increased responsiveness to tubocurarine when used concurrently with chlorothiazide sodium.
- Tubocurarine + Chlorthalidone— Chlorthalidone may increase the responsiveness to tubocurarine, potentially enhancing its neuromuscular blocking effects…
- Tubocurarine + Furosemide— Furosemide may antagonize the skeletal muscle relaxing effect of tubocurarine.
- Tubocurarine + Furosemide Injection 80 Mg/ 10 Ml— Furosemide has a tendency to antagonize the skeletal muscle relaxing effect of tubocurarine. Monitor for skeletal muscle…
- Tubocurarine + Furosemide, Benzalkonium Chloride— Furosemide has a tendency to antagonize the skeletal muscle-relaxing effect of tubocurarine.
- Tubocurarine + Hydrochlorothiazide— Possible increased responsiveness to the muscle relaxant may occur.
- Tubocurarine + Incobotulinumtoxina— Tubocurarine-type muscle relaxants may potentiate the effect of incobotulinumtoxina. Co-administer only with caution and…
- Tubocurarine + Irbesartan And Hydrochlorothiazide— Possible increased responsiveness to nondepolarizing skeletal muscle relaxant.
- Tubocurarine + Metoprolol Tartrate And Hydrochlorothiazide— Thiazides may increase the responsiveness to tubocurarine.
- Tubocurarine + Spironolactone— Possible increased responsiveness to the nondepolarizing muscle relaxant may result.
- Tubocurarine + Spironolactone And Hydrochlorothiazide— Possible increased responsiveness to the muscle relaxant may result.
- Tubocurarine + Triamterene And Hydrochlorothiazide— Thiazides have been shown to increase responsiveness to tubocurarine.